TIGAR/C12orf5 Antibody

Western Blot: TIGAR/C12orf5 Antibody [NBP2-24507] - Analysis of human TIGAR in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody.

Immunohistochemistry-Paraffin: TIGAR/C12orf5 Antibody [NBP2-24507] - Analysis of human brain, cerebellum using this antibody at 10 ug/ml.

Product Discontinued

TIGAR/C12orf5 Antibody Summary

• Immunogen: A portion of amino acids 220-270 of human TIGAR was used as the immunogen.
• Predicted Species: Mouse (94%), Rat (94%), Equine (94%), Bovine (94%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TIGAR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 1-3 ug/ml

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Opossum (88%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.2% Gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TIGAR/C12orf5 Antibody

• C12orf5
• chromosome 12 open reading frame 5
• EC 3.1.3.46
• probable fructose-2,6-bisphosphatase TIGAR
• TIGAR
• TIGARTP53-induced glycolysis and apoptosis regulator
• transactivated by NS3TP2 protein

Background

The TIGAR gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity tothe bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions byblocking glycolysis and d

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TIGAR
• Uniprot:
  • Q9NQ88(Human)