We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

TIGAR/C12orf5 Products

Antibodies
TIGAR/C12orf5 Antibody - BSA ...
TIGAR/C12orf5 Antibody - BSA Free
NBP2-24754
Species: Hu, Mu, Rt, Pm
Applications: WB, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Lysates
TIGAR/C12orf5 Overexpression ...
TIGAR/C12orf5 Overexpression Lysate
NBL1-08147
Species: Hu
Applications: WB
Proteins
Recombinant Human TIGAR/C12or ...
Recombinant Human TIGAR/C12orf5 Hi...
11008-TG
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Human TIGAR/C12or ...
Recombinant Human TIGAR/C12orf5 TA...
NBP2-35063
Species: Hu
Applications: PAGE, Bioactivity
TIGAR/C12orf5 Recombinant Pro ...
TIGAR/C12orf5 Recombinant Protein ...
NBP2-38462PEP
Species: Hu
Applications: AC

Description

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq]

Bioinformatics

Product By Gene ID 57103
Alternate Names
  • C12orf5
  • chromosome 12 open reading frame 5
  • EC 3.1.3.46
  • probable fructose-2,6-bisphosphatase TIGAR
  • TIGAR
  • TIGARTP53-induced glycolysis and apoptosis regulator
  • transactivated by NS3TP2 protein

Research Areas for TIGAR/C12orf5

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism