Thyroid Peroxidase Antibody (TPO34)

Product Discontinued

Thyroid Peroxidase Antibody (TPO34) Summary

• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with human thyroid peroxidase.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TPO
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunoassay
  • Sandwich ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: Recommended pairs for sandwich immunoassays (capture-detection): NBP1-50812 - NBP1-50813

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Thyroid Peroxidase Antibody (TPO34)

• EC 1.11.1
• MSA
• TDH2A
• thyroid microsomal antigen
• thyroid peroxidase
• thyroperoxidase
• TPXEC 1.11.1.8

Background

Thyroid Peroxidase (TPO) plays a central role in thyroid gland function. The enzyme catalyzes two important reactions of thyroid hormone synthesis: the iodination of tyrosine residues in thyroglobulin and phenoxy ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. A defect in this gene is thought to cause several disorders of thyroid hormonogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TPO