Thioredoxin Reductase 1/TRXR1 Antibody

Images

 
Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-33210] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-33210] - Paraffin-embedded SCM-1 xenograft, using antibody at 1:500 dilution.
Western Blot: Thioredoxin Reductase 1/TRXR1 Antibody [NBP1-33210] - Mouse liver lysate/extract 7. 5 % SDS-PAGE gel, antibody dilution 1:1000.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Thioredoxin Reductase 1/TRXR1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.
Localization
Cytoplasm, Isoform 4: Cytoplasm, Nucleus, Isoform 5: Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TXNRD1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Thioredoxin Reductase 1/TRXR1 Antibody

  • EC 1.8.1
  • EC 1.8.1.9
  • Gene associated with retinoic and IFN-induced mortality 12 protein
  • Gene associated with retinoic and interferon-induced mortality 12 protein
  • GRIM12
  • GRIM-12
  • GRIM-12TR1
  • KDRF
  • KM-102-derived reductase-like factor
  • MGC9145
  • oxidoreductase
  • Thioredoxin Reductase 1
  • thioredoxin reductase 1, cytoplasmic
  • thioredoxin reductase GRIM-12
  • Thioredoxin reductase TR1
  • TR
  • TR1
  • TRXR1
  • TRXRD1
  • TXNR
  • TXNRD1
  • TXNRTRXR1

Background

This protein is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TXNRD1
Entrez