TFII-I Antibody (PCRP-GTF2I-1A7)

Analysis of Protein Array containing more than 19,000 full-length human proteins using TFII-I antibody (PCRP-GTF2I-1A7)

Flow Cytometric Analysis of PFA-fixed HeLa cells. TFII-I antibody (PCRP-GTF2I-1A7) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).

• Reactivity: Hu
• Applications: Flow
• Clone: PCRP-GTF2I-1A7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

TFII-I Antibody (PCRP-GTF2I-1A7) Summary

• Description: Store at 2 to 8C. Non-hazardous. No MSDS required.
• Immunogen: Recombinant human TFII-I protein
• Localization: Nucleus.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: GTF2I
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-2ug/million cells
• Application Notes: Optimal dilution for a specific application should be determined.

Reactivity Notes

Predicted to react in Mouse, Rat and Chick.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for TFII-I Antibody (PCRP-GTF2I-1A7)

• BAP-135,135kD
• BAP135WBS
• Bruton tyrosine kinase-associated protein 135
• BTKAP1
• DIWS
• FLJ38776
• FLJ56355
• general transcription factor II, i
• general transcription factor IIi
• general transcription factor II-I
• GTFII-I
• IB291
• SPINBTK-associated protein 135
• TFII-ISRF-Phox1-interacting protein
• WBSCR6
• Williams-Beuren syndrome chromosome region 6

Background

TFII-I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GTF2I