TFII-I Antibody (PCRP-GTF2I-1A7) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: Flow
• Clone: PCRP-GTF2I-1A7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

TFII-I Antibody (PCRP-GTF2I-1A7) [Alexa Fluor® 350] Summary

• Immunogen: Recombinant human TFII-I protein
• Localization: Nucleus.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: GTF2I
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react in Mouse, Rat and Chick.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TFII-I Antibody (PCRP-GTF2I-1A7) [Alexa Fluor® 350]

• BAP-135,135kD
• BAP135WBS
• Bruton tyrosine kinase-associated protein 135
• BTKAP1
• DIWS
• FLJ38776
• FLJ56355
• general transcription factor II, i
• general transcription factor IIi
• general transcription factor II-I
• GTFII-I
• IB291
• SPINBTK-associated protein 135
• TFII-ISRF-Phox1-interacting protein
• WBSCR6
• Williams-Beuren syndrome chromosome region 6

Background

TFII-I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GTF2I