Tensin 4/CTEN Antibody (3B8) - Azide and BSA Free

Western Blot: Tensin 4/CTEN Antibody (3B8) [H00084951-M01] - Analysis of TNS4 expression in transfected 293T cell line by TNS4 monoclonal antibody (M01), clone 3B8.Lane 1: TNS4 transfected lysate(51.8 KDa).Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: Tensin 4/CTEN Antibody (3B8) [H00084951-M01] - Analysis of monoclonal antibody to TNS4 on HeLa cell . Antibody concentration 10 ug/ml.

Sandwich ELISA: Tensin 4/CTEN Antibody (3B8) [H00084951-M01] - Detection limit for recombinant GST tagged TNS4 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 3B8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Tensin 4/CTEN Antibody (3B8) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse Tensin 4/CTEN Antibody (3B8) - Azide and BSA Free (H00084951-M01) is a monoclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-Tensin 4/CTEN Antibody: Cited in 3 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: TNS4 (AAH18706, 1 a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRKWQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM
• Specificity: TNS4 - tensin 4
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TNS4
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It is also useful for immunofluorescence.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Tensin 4/CTEN Antibody (3B8) - Azide and BSA Free

• CTEN
• CTENC terminal tensin like
• C-terminal tensin-like protein
• FLJ14950
• Tensin 4
• tensin-4
• TNS4

Background

TNS4 may be involved in cell migration, cartilage development and in linking signal transduction pathways to thecytoskeleton . May promote apoptosis, via its cleavage by caspase-3

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Tensin 4/CTEN Antibody (H00084951-M01)(3)

Publications using H00084951-M01

• L Qin, X Cao, T Kaneko, C Voss, X Liu, G Wang, SS Li Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors The Journal of Biological Chemistry, 2021-09-02;0(0):101161. 2021-09-02 [PMID: 34480897]
• McHugh BJ, Murdoch A, Haslett C, Sethi T. Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration. PLoS One. 2012-07-05 [PMID: 22792288]
• Sakashita K, Mimori K, Tanaka F et al. Prognostic Relevance of Tensin4 Expression in Human Gastric Cancer. Ann Surg Oncol;15(9):2606-13. 2008-09-01 [PMID: 18612693]

Bioinformatics

• Gene Symbol: TNS4
• Entrez:
  • 84951(Human)
• OMIM:
  • 608385(Human)
• Uniprot:
  • AAH18706(Human)