TEM5/GPR124 Antibody

Images

 
Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Anti-GPR124 / TEM5 antibody IHC of human Prostate, Carcinoma Capillary Endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after ...read more
Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human colon carcinoma, neoplastic cells.
Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human lung, adenocarcinoma.
Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Anti-GPR124 / TEM5 antibody IHC of human Skin, Kaposis Sarcoma Tumor Endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after ...read more

Product Details

Summary
Reactivity Hu, MkSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

TEM5/GPR124 Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR124.
Localization
Membrane; multi pass membrane protein.
Specificity
Human GPR124. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Monkey (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR124
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Predicted cross-reactiivty based on sequence identity: Gibbon (100%), Marmoset (95%), Elephant (95%), Gorilla (89%), Canine (89%), Panda (89%), Bat (84%), Hamster (84%), Equine (84%), Porcine (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TEM5/GPR124 Antibody

  • DKFZp434C211
  • DKFZp434J0911
  • G protein-coupled receptor 124
  • GPR124
  • G-protein coupled receptor 124
  • KIAA1531
  • KIAA1531FLJ14390
  • TEM5
  • TEM5Tumor endothelial marker 5

Background

Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2. TEM5 expression has been documented in endothelial cells of tumors, including colon, brain, liver. Expression is restricted largely to endothelial cells (St Croix et al. 2000).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GPR124
Entrez
Uniprot