TEM5/GPR124 Antibody - BSA Free

Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Anti-GPR124 / TEM5 antibody IHC of human Prostate, Carcinoma Capillary Endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human colon carcinoma, neoplastic cells.

Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human lung, adenocarcinoma.

Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Anti-GPR124 / TEM5 antibody IHC of human Skin, Kaposis Sarcoma Tumor Endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

• Reactivity: Hu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

TEM5/GPR124 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 19 amino acid peptide from N-terminal extracellular domain of human TEM5/GPR124.
• Epitope: N-Terminus extracellular domain
• Localization: Membrane; multi pass membrane protein.
• Specificity: Human GPR124. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (95%), Primate (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADGRA2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2 - 5 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (95%), Gorilla (89%), Canine (89%), Bat (84%), Hamster (84%), Equine (84%), Porcine (84%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TEM5/GPR124 Antibody - BSA Free

• DKFZp434C211
• DKFZp434J0911
• G protein-coupled receptor 124
• GPR124
• G-protein coupled receptor 124
• KIAA1531
• KIAA1531FLJ14390
• TEM5
• TEM5Tumor endothelial marker 5

Background

Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2. TEM5 expression has been documented in endothelial cells of tumors, including colon, brain, liver. Expression is restricted largely to endothelial cells (St Croix et al. 2000).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRA2
• Entrez:
  • 25960(Human)
• Uniprot:
  • Q96PE1()