TCR V beta 5 Antibody (MEM-262) Summary
Human thymoma cell line HPB-ALL.
The antibody MEM-262 recognizes beta chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells. This subset is larger than that recognized by other V(beta5.3)-specific antibodies.
Protein A purified
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Packaging, Storage & Formulations
Store at 4C. Do not freeze.
PBS (pH 7.4)
15mM Sodium Azide
Protein A purified
- Western Blot 1:1000
- Flow Cytometry 1:10-1:1000
- Immunoprecipitation 1:50
Western Blot: Uniquely recognizes denatured TCR beta chains under the conditions
Alternate Names for TCR V beta 5 Antibody (MEM-262)
- T cell receptor beta locus
- T-cell antigen receptor, beta polypeptide, T-cell receptor, beta cluster
- T-cell receptor, beta cluster
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. The Vbeta5 TCR is a variant of the TCR beta chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. TCR Vbeta5 has been reported to recognize some staphylococcus bacterial superantigens.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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