TCF-12/HTF4 Antibody (OTI4D6) [Biotin]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI4D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Biotin

TCF-12/HTF4 Antibody (OTI4D6) [Biotin] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 1-250 of human TCF-12/HTF4 (NP_996919) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: TCF12
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TCF-12/HTF4 Antibody (OTI4D6) [Biotin]

• BHLHB20
• bHLHb20E-box-binding protein
• Class B basic helix-loop-helix protein 20
• HEB
• HEBDNA-binding protein HTF4
• helix-loop-helix transcription factor 4
• HsT17266
• HTF4
• HTF4TCF-12
• TCF12
• TCF-12
• transcription factor 12
• Transcription factor HTF-4

Background

TCF12 is encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TCF12