TAS1R1 Antibody - BSA Free

Immunohistochemistry-Paraffin: TAS1R1 Antibody [NLS1994] - Anti-T1R1 / TAS1R1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: TAS1R1 Antibody [NLS1994] - IHC staining of human testis.

Immunohistochemistry-Paraffin: TAS1R1 Antibody [NLS1994] - Analysis of anti-T1R1 / TAS1R1 antibody with human colon, carcinoma.

• Reactivity: Hu, Po, Bv, Ca, Eq, Mu, Rt, Fe, Ha, Pm, Pm, Rb
• Applications: IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

TAS1R1 Antibody - BSA Free Summary

• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human TAS1R1.
• Epitope: 3rd cytoplasmic domain
• Specificity: Human TAS1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TAS1R2 (69%).
• Predicted Species: Mouse (94%), Rat (94%), Hamster (94%), Primate (100%), Monkey (100%), Feline (100%), Rabbit (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAS1R1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1.25 - 2.5 ug/ml
• Control:

  TAS1R3 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Zebrafish (81%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Product can be stored undiluted at 4C for up to 1 month.

Alternate Names for TAS1R1 Antibody - BSA Free

• GPR70
• G-protein coupled receptor 70
• seven transmembrane helix receptor
• T1R1TR1G protein-coupled receptor 70
• taste receptor type 1 member 1
• taste receptor, type 1, member 1

Background

TAS1R1 is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene. The expression of this gene is largely restricted to taste buds in mammals. However, some ESTs have been isolated from liver, testis and bone.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAS1R1
• Entrez:
  • 80835(Human)
• Uniprot:
  • Q7RTX1(Human)