TAS1R1 Antibody

Images

 
Immunohistochemistry-Paraffin: TAS1R1 Antibody [NLS1994] - Anti-T1R1 / TAS1R1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Immunohistochemistry-Paraffin: TAS1R1 Antibody [NLS1994] - IHC staining of human testis.
Immunohistochemistry-Paraffin: TAS1R1 Antibody [NLS1994] - Analysis of anti-T1R1 / TAS1R1 antibody with human colon, carcinoma.

Product Details

Summary
Reactivity Hu, Po, Bv, Ca, Eq, Mu, Rt, Fe, Ha, Pm, Ma-Op, Pm, RbSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

TAS1R1 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human TAS1R1.
Specificity
Human TAS1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TAS1R2 (69%).
Predicted Species
Mouse (94%), Rat (94%), Hamster (94%), Primate (94%), Monkey (100%), Feline (100%), Opossum (94%), Rabbit (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TAS1R1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1.25 - 2.5 ug/ml
Control
TAS1R3 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Zebrafish (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TAS1R1 Antibody

  • GPR70
  • G-protein coupled receptor 70
  • seven transmembrane helix receptor
  • T1R1TR1G protein-coupled receptor 70
  • taste receptor type 1 member 1
  • taste receptor, type 1, member 1

Background

TAS1R1 is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene. The expression of this gene is largely restricted to taste buds in mammals. However, some ESTs have been isolated from liver, testis and bone.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Blogs on TAS1R1.

Taste Infographic: Explaining Taste from the Tongue to the Brain
The sense of taste involves the reaction of chemicals with nerve cells which send messages to the brain to create the perception of flavor. Learn more about taste and in the infographic below.Novus Biologicals offers research reagents mentioned in...  Read full blog post.

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Bioinformatics

Gene Symbol TAS1R1
Entrez
Uniprot