Tankyrase 1 Antibody [HRP]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: HRP

Tankyrase 1 Antibody [HRP] Summary

• Immunogen: E. coli-derived recombinant human Tankyrase 1
  Ala943-Gly1039
  Accession # O95271
• Specificity: Detects human Tankyrase 1 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: TNKS
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Antigen Affinity-purified

Alternate Names for Tankyrase 1 Antibody [HRP]

• EC 2.4.2.30
• PARP5A
• PARP-5a
• PARP5APARPL
• PARPL
• pART5
• Poly [ADP-ribose] polymerase 5A
• TANK1
• Tankyrase 1
• Tankyrase I
• tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
• tankyrase-1
• TIN1TANK1
• TINF1
• TINF1TNKS-1
• TNKS
• TNKS1TRF1-interacting ankyrin-related ADP-ribose polymerase

Background

The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNKS