Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Mu, Rt, Pm, Bv, Ch, RM, Xp
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Description
The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
8658 |
| Alternate Names |
- EC 2.4.2.30
- PARP-5a
- PARP5APARPL
- pART5
- Poly [ADP-ribose] polymerase 5A
- Tankyrase I
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
- tankyrase-1
- TIN1TANK1
- TINF1TNKS-1
- TNKS1TRF1-interacting ankyrin-related ADP-ribose polymerase
|
