TACE/ADAM17 Antibody (136133) [Unconjugated]

Images

 
HeLa human cervical epithelial carcinoma cell line was stained with Mouse Anti-Human TACE/ADAM17 Cytosolic Domain Monoclonal Antibody (Catalog # MAB21291, filled histogram) or isotype control antibody (Catalog # ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP, CyTOF-ready, Flow
Clone
136133
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

TACE/ADAM17 Antibody (136133) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human TACE/ADAM17
Asp695-Cys824
Accession # P78536
Specificity
Detects human TACE/ADAM17 Cytosolic Domain in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human ADAM33 is observed.
Details of Functionality
ActivityAssaywCitation not found None None None
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADAM17
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Immunoprecipitation 25 ug/mL
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells
Control
TACE/ADAM17 Lysate (NBP2-64810)
Publications
Read Publication using
MAB21291 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TACE/ADAM17 Antibody (136133) [Unconjugated]

  • ADAM 17
  • ADAM metallopeptidase domain 17
  • ADAM metallopeptidase domain 18
  • ADAM17
  • ADAM18
  • CD156b antigen
  • CD156b
  • CSVP
  • disintegrin and metalloproteinase domain-containing protein 17
  • EC 3.4.24.86
  • MGC71942
  • Snake venom-like protease
  • TACE
  • TACEcSVP
  • TNF-alpha convertase
  • TNF-alpha converting enzyme
  • TNF-alpha-converting enzyme
  • tumor necrosis factor, alpha, converting enzyme

Background

TACE (also known as ADAM17) is a type I membrane zinc protease of the ADAM family that functions as a major sheddase on the cell surface.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TACE/ADAM17 Antibody (MAB21291)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


Filter By Application
WB
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADAM17
Uniprot