Species: Hu
Applications: WB, Flow, IP, CyTOF-ready, KO
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt, Po, Ca
Applications: WB, IHC, KO
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Hu
Applications: Enzyme Activity
Species: Mu
Applications: Enzyme Activity
Species: Hu
Applications: WB
Description
ADAM17 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Bioinformatics
| Entrez |
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
6868 |
| Alternate Names |
- ADAM 17
- ADAM metallopeptidase domain 17
- ADAM metallopeptidase domain 18
- ADAM18
- CD156b antigen
- CD156B
- CSVP
- disintegrin and metalloproteinase domain-containing protein 17
- EC 3.4.24.86
- MGC71942
- Snake venom-like protease
- TACEcSVP
- TNF-alpha convertase
- TNF-alpha converting enzyme
- TNF-alpha-converting enzyme
- tumor necrosis factor, alpha, converting enzyme
|
![Flow Cytometry TACE/ADAM17 Antibody (111633) [Unconjugated]](http://images.novusbio.com/fullsize2/TACE_MAB9301_Flow_Cytometry_16093.jpg)
![Knockout Validated TACE/ADAM17 Antibody (111633) [Unconjugated]](http://images.novusbio.com/fullsize2/TACE_MAB9301_Knockout_Validated_22403.jpg)
![Flow Cytometry TACE/ADAM17 Antibody (111633) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab9301_human-tace-adam17-ectodomain-mab-clone-111633-flow-cytometry-412024133519..jpg)
![N/A TACE/ADAM17 [Biotin]](http://images.novusbio.com/fullsize2/DATA_TACE_DY930_ELISA_2267.jpg)
