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ADAM17 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
![Flow Cytometry TACE/ADAM17 Antibody (111633) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/TACE_MAB9301_Flow_Cytometry_16093.jpg)
![Knockout Validated TACE/ADAM17 Antibody (111633) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/TACE_MAB9301_Knockout_Validated_22403.jpg)
![Flow Cytometry TACE/ADAM17 Antibody (111633) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab9301_human-tace-adam17-ectodomain-mab-clone-111633-flow-cytometry-412024133519..jpg)
![N/A TACE/ADAM17 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_TACE_DY930_ELISA_2267.jpg)
![SEC-MALS TACE/ADAM17 [Unconjugated]](http://images.novusbio.com/fullsize/930-adb_recombinant-human-tace-adam17-protein-cf-sec-mals-134202611180.jpg)