t-Plasminogen Activator/tPA Antibody - BSA Free

Immunohistochemistry-Paraffin: t-Plasminogen Activator/tPA Antibody [NBP1-87491] - Staining of human fallopian tube shows moderate to strong positivity in plasma.

Immunohistochemistry-Paraffin: t-Plasminogen Activator/tPA Antibody [NBP1-87491] - Staining of human kidney shows moderate to strong extracellular space positivity in cells in tubules.

Immunohistochemistry-Paraffin: t-Plasminogen Activator/tPA Antibody [NBP1-87491] - Staining of human skin shows no cytoplasmic positivity in epidermal cells as expected.

Immunohistochemistry-Paraffin: t-Plasminogen Activator/tPA Antibody [NBP1-87491] - Staining of human placenta shows strong extracelluar space positivity in trophoblastic cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

t-Plasminogen Activator/tPA Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLF
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLAT
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  t-Plasminogen Activator/tPA Protein (NBP1-87491PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for t-Plasminogen Activator/tPA Antibody - BSA Free

• Alteplase
• DKFZp686I03148
• EC 3.4.21
• EC 3.4.21.68
• plasminogen activator, tissue type
• plasminogen activator, tissue
• PLAT
• Reteplase
• tissue plasminogen activator (t-PA)
• tissue-type plasminogen activator
• TPA
• T-PA
• tPlasminogen Activator
• t-Plasminogen Activator

Background

Tissue plasminogen activator (tPA) is a serine protease which converts the abundant proenzyme plasminogen to active plasmin. It plays a key role in thrombolysis (1) and several neurobiological processes (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for t-Plasminogen Activator/tPA Antibody (NBP1-87491)(1)

Publication using NBP1-87491

• Kato BS, Nicholson G, Neiman M et al. Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. Proteome Sci 2011-11-17 [PMID: 22093360]

FAQs for t-Plasminogen Activator/tPA Antibody (NBP1-87491). (Showing 1 - 1 of 1 FAQ).

1. For the following antibodies our customer would like to find the percentage of purity: Tissue Plasminogen Activator Antibody (NBP1-87491), and Tissue Plasminogen Activator Antibody (NBP1-57814).
   • Both of these antibodies are affinity purified, so the purity is expected to be greater than 95%.

Bioinformatics

• Gene Symbol: PLAT