SYT17 Antibody - Azide and BSA Free

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

SYT17 Antibody - Azide and BSA Free Summary

• Description: Novus Biologicals Rabbit SYT17 Antibody - Azide and BSA Free (NBP1-03494) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A synthetic peptide from the internal region of human SYT17 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
• Localization: Subcellular location: membrane; peripheral membrane protein.; tissue specificity: expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra, and pituitary), kidney, and prostate. expressed in fetal br
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SYT17
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 10-50 ug/ml
  • Immunohistochemistry-Frozen 10-50 ug/ml
  • Western Blot 10-50 ug/ml
• Control:

  SYT17 Overexpression Lysate

Reactivity Notes

The antigen is homologous in Mouse and Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Ammonium sulfate precipitation
• Reconstitution Instructions: Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.

Alternate Names for SYT17 Antibody - Azide and BSA Free

• B/K protein
• synaptotagmin XVIIProtein B/K
• synaptotagmin-17
• sytXVII

Background

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SYT17
• Entrez:
  • 51760(Human)
  • 110058(Mouse)
  • 192189(Rat)
• Uniprot:
  • Q9BSW7(Human)
  • Q920M7(Mouse)
  • Q62807(Rat)