SYT17 Antibody

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Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.
Immunohistochemistry: SYT17 Antibody [NBP1-03494] - IHC on mouse brain (cryo section) using Rabbit antibody to internal region of Synaptotagmin 17 (SYT17): IgG at a concentration of 50 ug/ml incubated overnight at 4C.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-Fr
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

SYT17 Antibody Summary

Immunogen
A synthetic peptide from the internal part of human Synaptotagmin 17 (SYT17) conjugated to an immunogenic carrier protein was used as the immunogen.
Localization
Subcellular location: membrane; peripheral membrane protein.; tissue specificity: expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra, and pituitary), kidney, and prostate. expressed in fetal br
Specificity
SYT17.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYT17
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 10-50 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 10-50 ug/ml
Positive Control
SYT17 Lysate (NBL1-16650)

Reactivity Notes

Human. The antigen is homologous in mouse and rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.

Alternate Names for SYT17 Antibody

  • B/K protein
  • synaptotagmin XVIIProtein B/K
  • synaptotagmin-17
  • sytXVII

Background

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SYT17
Entrez
Uniprot