Rabphilin 3A Antibody

Images

 
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry: Rabphilin 3A Antibody [NBP1-87940] - Staining of human cerebellum shows cytoplasmic positivity in purkinje cells and cells of molecular layer.
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human pancreas shows low expression as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining in human cerebral cortex and pancreas tissues using anti-RPH3A antibody. Corresponding RPH3A RNA-seq data are ...read more
Orthogonal Strategies: Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Analysis in human cerebral cortex and skeletal muscle tissues. Corresponding Rabphilin 3A RNA-seq data are presented for ...read more
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human cerebellum shows moderate positivity in neuropil.
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human cerebral cortex shows strong positivity in neuropil.
Immunohistochemistry-Paraffin: Rabphilin 3A Antibody [NBP1-87940] - Staining of human kidney shows no positivity in cells in tubules as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Rabphilin 3A Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RPH3A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Rabphilin 3A Protein (NBP1-87940PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Rabphilin 3A Antibody

  • Exophilin-1
  • KIAA0985exophilin-1
  • rabphilin 3A homolog (mouse)
  • rabphilin
  • rabphilin-3A

Background

Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994; Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995; Foletti and Scheller, 2001).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RPH3A