Synaptotagmin 1 Antibody (ASV48) [DyLight 680]

• Reactivity: Rt
• Applications: WB, IHC, IP, ICC/IF, KO
• Clone: ASV48
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 680

Synaptotagmin 1 Antibody (ASV48) [DyLight 680] Summary

• Immunogen: Rat brain synaptic plasma membranes
• Specificity: Detects Synaptotagmin‑1 from rat, mouse, human, chicken, Xenopus, and fish.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SYT1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Immunoprecipitation
  • Knockout Validated
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Synaptotagmin 1 Antibody (ASV48) [DyLight 680]

• DKFZp781D2042
• P65
• SVP65
• synaptotagmin Isynaptotagmin 1
• Synaptotagmin1
• Synaptotagmin-1
• SYT
• SYT1
• sytI

Background

Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001; Wang et al., 2003). Moreover recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999; Lee et al., 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SYT1