Synaptotagmin 1 Antibody (ASV48) [mFluor Violet 610 SE]

• Reactivity: Rt
• Applications: WB, IHC, IP, ICC/IF, KO
• Clone: ASV48
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

Synaptotagmin 1 Antibody (ASV48) [mFluor Violet 610 SE] Summary

• Immunogen: Rat brain synaptic plasma membranes
• Specificity: Detects Synaptotagmin‑1 from rat, mouse, human, chicken, Xenopus, and fish.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SYT1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Immunoprecipitation
  • Knockout Validated
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Synaptotagmin 1 Antibody (ASV48) [mFluor Violet 610 SE]

• DKFZp781D2042
• P65
• SVP65
• synaptotagmin Isynaptotagmin 1
• Synaptotagmin1
• Synaptotagmin-1
• SYT
• SYT1
• sytI

Background

Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001; Wang et al., 2003). Moreover recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999; Lee et al., 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SYT1