Synaptogyrin 3 Antibody

Images

 
Western Blot: Synaptogyrin 3 Antibody [NBP1-77102] - Mouse brain tissue lysate at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: Synaptogyrin 3 Antibody [NBP1-77102] - Rat brain tissue with SYNGR3 antibody at 2.5 ug/mL.
Immunofluorescence: Synaptogyrin 3 Antibody [NBP1-77102] - Immunofluorescence of SYNGR3 in Rat Brain cells with SYNGR3 antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Synaptogyrin 3 Antibody Summary

Immunogen
Antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SYNGR3. The immunogen is located within the last 50 amino acids of SYNGR3.
Marker
Synaptic Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SYNGR3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1 - 2 ug/mL
  • ELISA 1:100-1:2000
  • Immunohistochemistry 2.5 ug/mL
  • Immunohistochemistry-Paraffin 2.5 ug/mL
  • Immunofluorescence 20 ug/ml
Control Peptide
Synaptogyrin 3 Peptide (NBP1-77102PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Synaptogyrin 3 Antibody

  • MGC20003
  • synaptogyrin 3
  • synaptogyrin-3

Background

Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SYNGR3
Uniprot