Synaptogyrin 3 Antibody - BSA Free

Western Blot: Synaptogyrin 3 Antibody [NBP1-77102] - Mouse brain tissue lysate at (A) 1 and (B) 2 ug/mL .

Immunohistochemistry-Paraffin: Synaptogyrin 3 Antibody [NBP1-77102] - Rat brain tissue with SYNGR3 antibody at 2.5 ug/mL.

Immunocytochemistry/ Immunofluorescence: Synaptogyrin 3 Antibody - BSA Free [NBP1-77102] - Immunofluorescence of Synaptogyrin 3 in Rat Brain cells with Synaptogyrin 3 antibody at 20 u/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Synaptogyrin 3 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SYNGR3. The immunogen is located within the last 50 amino acids of SYNGR3. Amino Acid Squence: ETYQSPFFTETLDTSPKGY
• Marker: Synaptic Marker
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SYNGR3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  Synaptogyrin 3 Peptide (NBP1-77102PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (89%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Synaptogyrin 3 Antibody - BSA Free

• MGC20003
• synaptogyrin 3
• synaptogyrin-3

Background

Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Synaptogyrin 3 Antibody (NBP1-77102)(1)

Publication using NBP1-77102

• Lin NH, Goh A, Lin SH et al. Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo Journal of Alzheimer's disease reports 2023-01-27 [PMID: 36777330] (WB, ICC/IF, Human)

Bioinformatics

• Gene Symbol: SYNGR3
• Uniprot:
  • NP_004200(Human)