SWAP70 Antibody

Western Blot: SWAP70 Antibody [NBP2-24654] - analysis of SWAP70 in human spleen lysate in the 1) absence and 2) presence of immunizing peptide using SWAP70 antibody at 0.25 ug/ml.

Immunohistochemistry-Paraffin: SWAP70 Antibody [NBP2-24654] - Formalin-fixed paraffin-embedded human tonsil germinal center stained with SWAP70 antibody at 10 ug/ml. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

• Reactivity: Hu, Mu, Rt, Bv, Ca, Ma-Op, Ze
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SWAP70 Antibody Summary

• Description: Novus Biologicals Rabbit SWAP70 Antibody (NBP2-24654) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: A portion of amino acids 1-50 of human SWAP70 was used as the immunogen for the antibody.
• Predicted Species: Mouse (92%), Rat (100%), Canine (92%), Zebrafish (100%), Opossum (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SWAP70
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 0.25-0.50 ug/ml

Reactivity Notes

The amino acid sequence used as immunogen for the antibody is 85% homologous in Chicken.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for SWAP70 Antibody

• KIAA0640SWAP-70FLJ39540
• SWAP switching B-cell complex 70kDa subunit
• SWAP70
• switch-associated protein 70

Background

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SWAP70
• Uniprot:
  • Q9UH65()