Recombinant Human SUMO3 Protein

Product Discontinued

Recombinant Human SUMO3 Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-92 of Human SUMO3
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: SUMO3
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 12.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl, 1 mM DTT
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human SUMO3 Protein

• SMT3 (suppressor of mif two 3, yeast) homolog 1
• SMT3 homolog 1
• SMT3 suppressor of mif two 3 homolog 1
• SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
• SMT3 suppressor of mif two 3 homolog 3 (yeast)
• SMT3A
• SMT3B
• SMT3H1
• SMT3H1small ubiquitin-related modifier 3
• SUMO-2
• SUMO3
• SUMO-3
• ubiquitin-like protein SMT3A
• Ubiquitin-like protein SMT3B

Background

SUMO3, also known as small ubiquitin-related modifier 3, is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO3 protein participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It regulates amyloid beta generation and may be critical in the onset or progression of Alzheimer's disease. Recombinant human SUMO3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SUMO3