STAT5b Antibody (1A1)

Images

 
Western Blot: STAT5b Antibody (1A1) [H00006777-M01] - STAT5B monoclonal antibody (M01), clone 1A1 Analysis of STAT5B expression in Hela S3 NE.
Immunocytochemistry/ Immunofluorescence: STAT5b Antibody (1A1) [H00006777-M01] - Analysis of monoclonal antibody to STAT5B on HeLa cell. Antibody concentration 10 ug/ml.
Western Blot: STAT5b Antibody (1A1) [H00006777-M01] - Analysis of STAT5B expression in transfected 293T cell line by STAT5B monoclonal antibody (M01), clone 1A1.Lane 1: STAT5B transfected lysate(44.9 KDa).Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
1A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

STAT5b Antibody (1A1) Summary

Immunogen
STAT5B (AAH20868, 1 a.a. - 390 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRK
Localization
Cytoplasmic and Nuclear: Translocated into the nucleus in response to phosphorylation.
Specificity
STAT5B - signal transducer and activator of transcription 5B
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
STAT5B
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for STAT5b Antibody (1A1)

  • signal transducer and activator of transcription 5B
  • STAT5
  • STAT5b
  • transcription factor STAT5B

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol STAT5B
Entrez
OMIM
Uniprot