STAT5b Products

Antibodies
STAT5b Antibody [Unconjugated ...
STAT5b Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, IP, CyTOF-ready, Flow, ICC/IF, KO
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
STAT5b Antibody (SD08-08)
STAT5b Antibody (SD08-08)
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
STAT5b Antibody (1032E) [Unco ...
STAT5b Antibody (1032E) [Unconjuga...
MAB15841
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, KO
Host: Rabbit Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Rat STAT5b ELISA Kit (Colorim ...
Rat STAT5b ELISA Kit (Colorimetric)
NBP2-80282
Species: Rt
Applications: ELISA
Lysates
STAT5b 293T Cell Transient Ov ...
STAT5b 293T Cell Transient Overexp...
H00006777-T01
Species: Hu
Applications: WB
STAT5b 293T Cell Transient Ov ...
STAT5b 293T Cell Transient Overexp...
H00006777-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human STAT5b GST ...
Recombinant Human STAT5b GST (N-Te...
H00006777-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Recombinant Human STAT5b GST ...
Recombinant Human STAT5b GST (N-Te...
H00006777-Q01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP

Description

STAT5B is encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 6777
Alternate Names
  • transcription factor STAT5B
  • STAT5
  • signal transducer and activator of transcription 5B

Research Areas for STAT5b

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction

Bioinformatics Tool for STAT5b

Discover related pathways, diseases and genes to STAT5b. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related STAT5b Blog Posts

Check out the latest blog posts on STAT5b.
Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...    Read more.
Read more STAT5b related blogs.