STAT5b Products

Antibodies
STAT5b Antibody (1032E) [Unco ...
STAT5b Antibody (1032E) [Unconjuga...
MAB15841
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
Host: Rabbit Monoclonal
STAT5b Antibody [Unconjugated ...
STAT5b Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, IP, ICC, ICFlow
Host: Rabbit Polyclonal
STAT5b Antibody (389215)
STAT5b Antibody (389215)
MAB1584
Species: Hu
Applications: WB, ICFlow
Host: Mouse Monoclonal
Antibody Pairs
STAT5b Antibody Pair
STAT5b Antibody Pair
H00006777-PW1
Species: Hu
Applications: WB, IP
Lysates
STAT5b Overexpression Lysate ...
STAT5b Overexpression Lysate (Dena...
H00006777-T01
Species: Hu
Applications: WB
STAT5b Overexpression Lysate ...
STAT5b Overexpression Lysate (Dena...
H00006777-T02
Species: Hu
Applications: WB
Proteins
STAT5b Partial Recombinant Pr ...
STAT5b Partial Recombinant Protein
H00006777-Q01
Species: Hu
Applications: WB, ELISA, PA
STAT5b Recombinant Protein
STAT5b Recombinant Protein
H00006777-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
STAT5b RNAi
STAT5b RNAi
H00006777-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

STAT5B is encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 6777
Alternate Names
  • transcription factor STAT5B
  • STAT5
  • signal transducer and activator of transcription 5B

Research Areas for STAT5b

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction

Bioinformatics Tool for STAT5b

Discover related pathways, diseases and genes to STAT5b. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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