Home » STAT5b Products

We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

Register on R&D Systems

STAT5b Products

Antibodies
STAT5b Antibody [Unconjugated ...
STAT5b Antibody [Unconjugated]
AF1584
HAF008). A specific band was detected for STAT5b at approximately 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot STAT5b Antibody [Unconjugated]
NL004) and counterstained with DAPI(blue). Specific staining was localized to cytoplasm and nucleus. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry STAT5b Antibody [Unconjugated]
285-IF) for 15 minutes. STAT5b was immunoprecipitated from lysates of 5 x 106cells following incubation with 2 µg Rabbit Anti-Human/Mouse STAT5b Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1584) for 1 hour at room temperature. STAT5b-antibody complexes were absorbed using Protein A sepharose (Invitrogen, Catalog # 10-1041). Immunoprecipitated STAT5b was detected by Western blot using 1 µg/mL Human Phospho-STAT5a/b (Y699) Antigen Affinity-purified Polyclonal Antibody (AF4190). View our recommended buffer recipes for immunoprecipitation." class="big_lightbox" target="_blank"> Immunoprecipitation STAT5b Antibody [Unconjugated]
AB-105-C, open histogram), followed by Allophycocyanin-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # F0111). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with methanol." class="big_lightbox" target="_blank"> Intracellular Staining by Flow Cytometry STAT5b Antibody [Unconjugated]
Simple Western STAT5b Antibody [Unconjugated]
HAF008). A specific band was detected for STAT5b at approximately 90 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated STAT5b Antibody [Unconjugated]
Knockout Validated STAT5b Antibody [Unconjugated]
Immunoprecipitation STAT5b Antibody [Unconjugated]
Species: Hu, Mu
Applications: WB, Simple Western, IP, CyTOF-ready, Flow, ICC/IF, KO
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Carrier Free AF1584-SP
STAT5b Antibody (1032E) [Unco ...
STAT5b Antibody (1032E) [Unconjuga...
MAB15841
HAF008). A specific band was detected for STAT5b at approximately 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot STAT5b Antibody (1032E) [Unconjugated]
NL004) and counterstained with DAPI (blue). Specific staining was localized to nuclei and cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Immunocytochemistry STAT5b Antibody (1032E) [Unconjugated]
Simple Western STAT5b Antibody (1032E) [Unconjugated]
NL004) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm and nuclei. View our protocol for Fluorescent ICC Staining of Cells on Coverslips." class="big_lightbox" target="_blank"> Knockout Validated STAT5b Antibody (1032E) [Unconjugated]
HAF008). A specific band was detected for STAT5b at approximately 85 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the STAT5b knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated STAT5b Antibody (1032E) [Unconjugated]
Knockout Validated STAT5b Antibody (1032E) [Unconjugated]
Immunoprecipitation STAT5b Antibody (1032E) [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IP, ICC/IF, KO
Host: Rabbit Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB15841U-100UG
Alexa Fluor 405 FAB15841V-100UG
Alexa Fluor 488 FAB15841G-100UG
Alexa Fluor 532 FAB15841X-100UG
Alexa Fluor 594 FAB15841T-100UG
Alexa Fluor 647 FAB15841R-100UG
Alexa Fluor 700 FAB15841N-100UG
Alexa Fluor 750 FAB15841S-100UG
Alexa Fluor Plus 405 FAB15841AFP405-100UG
Alexa Fluor Plus 488 FAB15841AFP488-100UG
Alexa Fluor Plus 555 FAB15841AFP555-100UG
Alexa Fluor Plus 594 FAB15841AFP594-100UG
Alexa Fluor Plus 647 FAB15841AFP647-100UG
Alexa Fluor Plus 680 FAB15841AFP680-100UG
Allophycocyanin FAB15841A
Biotin FAB15841B
CoraFluor 1 FAB15841CL1
DyLight 350 FAB15841D
DyLight 405 FAB15841E
DyLight 488 FAB15841K
DyLight 550 FAB15841L
DyLight 594 FAB15841M
DyLight 650 FAB15841W
DyLight 680 FAB15841Y
DyLight 755 FAB15841Z
FITC FAB15841F
HRP FAB15841H
Janelia Fluor 525 FAB15841JF525
Janelia Fluor 549 FAB15841I
Janelia Fluor 646 FAB15841J
Janelia Fluor 669 FAB15841JF669
PE FAB15841P
PerCP FAB15841C
mFluor Violet 450 SE FAB15841MFV450
mFluor Violet 500 SE FAB15841MFV500
mFluor Violet 610 SE FAB15841MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB15841-SP
STAT5b Antibody (389215) [Unc ...
STAT5b Antibody (389215) [Unconjug...
MAB1584
HAF018). A specific band was detected for STAT5b at approximately 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Western Blot STAT5b Antibody (389215) [Unconjugated]
MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (F0101B)." class="big_lightbox" target="_blank"> Intracellular Staining by Flow Cytometry STAT5b Antibody (389215) [Unconjugated]
Simple Western STAT5b Antibody (389215) [Unconjugated]
HAF018). A specific band was detected for STAT5b at approximately 90 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (Catalog # MAB5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank"> Knockout Validated STAT5b Antibody (389215) [Unconjugated]
Immunoprecipitation STAT5b Antibody (389215) [Unconjugated]
Species: Hu
Applications: WB, Simple Western, IP, CyTOF-ready, Flow, KO
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 IC1584U-100UG
Alexa Fluor 405 IC1584V-100UG
Alexa Fluor 488 IC1584G-100UG
Alexa Fluor 532 FAB1584X
Alexa Fluor 594 IC1584T-100UG
Alexa Fluor 647 IC1584R-100UG
Alexa Fluor 700 IC1584N-100UG
Alexa Fluor 750 IC1584S-100UG
Alexa Fluor Plus 405 FAB1584AFP405-100UG
Alexa Fluor Plus 488 FAB1584AFP488-100UG
Alexa Fluor Plus 555 FAB1584AFP555-100UG
Alexa Fluor Plus 594 FAB1584AFP594-100UG
Alexa Fluor Plus 647 FAB1584AFP647-100UG
Alexa Fluor Plus 680 FAB1584AFP680-100UG
Allophycocyanin FAB1584A
Biotin FAB1584B
CoraFluor 1 FAB1584CL1
DyLight 350 FAB1584D
DyLight 405 FAB1584E
DyLight 488 FAB1584K
DyLight 550 FAB1584L
DyLight 594 FAB1584M
DyLight 650 FAB1584W
DyLight 680 FAB1584Y
DyLight 755 FAB1584Z
FITC FAB1584F
HRP FAB1584H
Janelia Fluor 525 FAB1584JF525
Janelia Fluor 549 FAB1584I
Janelia Fluor 646 FAB1584J
Janelia Fluor 669 FAB1584JF669
PE FAB1584P
PerCP FAB1584C
mFluor Violet 450 SE FAB1584MFV450
mFluor Violet 500 SE FAB1584MFV500
mFluor Violet 610 SE FAB1584MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB1584-SP
Carrier Free IC1584U-100UG
Carrier Free IC1584T-100UG
Carrier Free IC1584S-100UG
Carrier Free IC1584R-100UG
Carrier Free IC1584N-100UG
Carrier Free IC1584G-100UG
Carrier Free IC1584V-100UG
Read More
Read More
Read More
See All STAT5b Products
We have 18 STAT5b Antibodies
ELISA Kits
Rat STAT5b ELISA Kit (Colorim ...
Rat STAT5b ELISA Kit (Colorimetric)
NBP2-80282
ELISA Rat STAT5b ELISA Kit (Colorimetric)
ELISA Rat STAT5b ELISA Kit (Colorimetric)
Species: Rt
Applications: ELISA
Human STAT5b ELISA Kit (Color ...
Human STAT5b ELISA Kit (Colorimetric)
NBP3-53603
ELISA Human STAT5b ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Human STAT5b - Ready-To-Use ...
Human STAT5b - Ready-To-Use ELISA...
NBP3-56070
ELISA Human STAT5b - Ready-To-Use ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Read More
Read More
Read More
See All STAT5b Products
We have 3 STAT5b ELISA Kits
Proteins
Recombinant Human STAT5b GST ...
Recombinant Human STAT5b GST (N-Te...
H00006777-P01
SDS-Page Recombinant Human STAT5b GST (N-Term) Protein
Species: Hu
Applications: WB, ELISA, Endotoxin, PAGE, AP
Read More
See All STAT5b Products
We have 1 STAT5b Protein

Description

STAT5B is encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Bioinformatics

Entrez
20851
Mouse
25126
Rat
6777
Human
Uniprot
AAH20868
Human
AAH20868.1
Human
NP_036580
Human
P51692
Human
Product By Gene ID 6777
Alternate Names
  • signal transducer and activator of transcription 5B
  • STAT5
  • transcription factor STAT5B

Research Areas for STAT5b

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction

Related STAT5b Blog Posts

Check out the latest blog posts on STAT5b.
Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...    Read more.
Read more STAT5b related blogs.