Stanniocalcin 1/STC-1 Antibody (4H4)

Western Blot: Stanniocalcin 1/STC-1 Antibody (4H4) [H00006781-M01] - Detection against Immunogen (37.51 KDa) .

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 4H4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Stanniocalcin 1/STC-1 Antibody (4H4) Summary

• Immunogen: STC1 (AAH29044, 141 a.a. ~ 247 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NPEAITEVVQLPNHFSNRYYNRLVRSLLECDEDTVSTIRDSLMEKIGPNMASLFHILQTDHCAQTHPRADFNRRRTNEPQKLKVLLRNLRGEEDSPSHIKRTSHESA
• Localization: Secreted
• Specificity: STC1 - stanniocalcin 1
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: STC1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Stanniocalcin 1/STC-1 Antibody (4H4)

• Stanniocalcin 1
• stanniocalcin-1
• STC1
• STC-1
• STCSTC-1

Background

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Stanniocalcin 1/STC-1 Antibody (H00006781-M01)(1)

Publication using H00006781-M01

• dos Santos MT, Trindade DM, Goncalves Kde A et al. Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase. Mol Biosyst. 2010-11-01 [PMID: 21042649]

Bioinformatics

• Gene Symbol: STC1
• Entrez:
  • 6781(Human)
• OMIM:
  • 601185(Human)
• Uniprot:
  • AAH29044(Human)