Stanniocalcin 1/STC-1 Products

Description

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.

Bioinformatics

Entrez	6781 Human
Uniprot	AAH29044 Human
Product By Gene ID	6781
Alternate Names	Stanniocalcin 1 stanniocalcin-1 STC1 STC-1 STCSTC-1

Research Areas for Stanniocalcin 1/STC-1

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Signal Transduction