SSBIP1/SOSS-C Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

SSBIP1/SOSS-C Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human INIP.
  
  

  Source: E. coli

  Amino Acid Sequence: KEKRKLLMQNQSSTNHPGASIALSRPSLNKDFRDHAEQQHIAAQQKAALQHAHAHSSGYFITQDSAFGNL

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: INIP
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-81682.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 25 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for SSBIP1/SOSS-C Recombinant Protein Antigen

• chromosome 9 open reading frame 80
• HSPC043
• hSSB-interacting protein 1
• hSSBIP1
• minute INTS3/hSSB-associated element
• MISE
• Sensor of single-strand DNA complex subunit C
• Sensor of ssDNA subunit C
• Single-stranded DNA-binding protein-interacting protein 1
• SOSS complex subunit C
• SOSSC
• SOSS-C
• SSB-interacting protein 1
• SSBIP1

Background

C9orf80 is a component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promoteDNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influencesdiverse endpoints in the cellula

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: INIP