SPG3A Antibody (1B9)

Images

 
Western Blot: SPG3A Antibody (1B9) [H00051062-M03] - Analysis of SPG3A expression in PC-12 (Cat # L012V1).
Western Blot: SPG3A Antibody (1B9) [H00051062-M03] - Analysis of SPG3A expression in IMR-32 (Cat # L008V1).
ELISA: SPG3A Antibody (1B9) [H00051062-M03] - Detection limit for recombinant GST tagged SPG3A is approximately 1ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ELISA
Clone
1B9
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

SPG3A Antibody (1B9) Summary

Immunogen
SPG3A (NP_056999, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag.MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWV
Specificity
SPG3A - spastic paraplegia 3A (autosomal dominant)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ATL1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human, Rat.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SPG3A Antibody (1B9)

  • AD-FSP
  • atlastin GTPase 1
  • atlastin1
  • atlastin-1
  • Brain-specific GTP-binding protein
  • EC 3.6.5.-
  • FSP1
  • GBP3
  • GBP-3
  • GTP-binding protein 3
  • Guanine nucleotide-binding protein 3
  • guanylate-binding protein 3
  • Spastic paraplegia 3 protein A
  • spastic paraplegia 3A (autosomal dominant)
  • SPG3
  • SPG3AhGBP3

Background

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ELISA

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ATL1
Entrez
OMIM
Uniprot