SOX7 Antibody (288610)

• Reactivity: Hu
• Applications: WB
• Clone: 288610
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

SOX7 Antibody (288610) Summary

• Immunogen: E. coli-derived recombinant human SOX7
  Ser249-Ala345
  Accession # Q9BT81
• Specificity: Detects human SOX7 in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant human SOX2, 3, 9, 10, or 17.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: SOX7
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX7 Antibody (288610)

• MGC10895
• SOX7 transcription factor
• SOX7
• SRY (sex determining region Y)-box 7
• transcription factor SOX-7

Background

SOX7 belongs to the Sox (SRY-like HMG-box gene) family of transcription factors with diverse roles in development. SOX7 has been suggested to play a crucial role in parietal endoderm differentiation. SOX7 is expressed in many embryonic and adult tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SOX7 Antibody (MAB2766)(2)

Publications using MAB2766

• Ning Guan, Rui Wang, Xu Feng, Chenguang Li, Wenshi Guo Long non‑coding RNA NBAT1 inhibits the progression of glioma through the miR‑21/SOX7 axis Oncology Letters 7/9/2020 [PMID: 32782620]
• Zhang Y, Huang S, Dong W, Li L, Feng Y, Pan L, Han Z, Wang X, Ren G, Su D, Huang B, Lu J SOX7, down-regulated in colorectal cancer, induces apoptosis and inhibits proliferation of colorectal cancer cells. Cancer Lett., 2008-12-23;277(1):29-37. 2008-12-23 [PMID: 19108950] (Western Blot, Human)

Bioinformatics

• Gene Symbol: SOX7
• Uniprot:
  • Q9BT81()