SOCS-6 Antibody [FITC]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: FITC

SOCS-6 Antibody [FITC] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human SOCS-6
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SOCS6
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Alternate Names for SOCS-6 Antibody [FITC]

• CIS4CIS-4
• Cytokine-inducible SH2 protein 4
• HSPC060
• SOCS4Cish4
• SOCS6
• SOCS-6
• SSI4SOCS-6
• STAI4
• STAT induced STAT inhibitor-4
• STAT4
• STATI4
• Suppressor of cytokine signaling 4SOCS-4
• suppressor of cytokine signaling 6

Background

SOCS6 is encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOCS6