SOCS-6 Products

Description

SOCS6 is encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Bioinformatics

Entrez	9306 Human
Uniprot	AAH20082 Human NM_004232 Human NP_004223 Human NP_004223.2 Human
Product By Gene ID	9306
Alternate Names	CIS4CIS-4 Cytokine-inducible SH2 protein 4 HSPC060 SOCS4Cish4 SSI4SOCS-6 STAI4 STAT induced STAT inhibitor-4 STAT4 STATI4 Suppressor of cytokine signaling 4SOCS-4 suppressor of cytokine signaling 6

Research Areas for SOCS-6

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Signal Transduction