SNF5 Antibody

Western Blot: SNF5 Antibody [H00006598-B01P] - Analysis of SMARCB1 expression in 293.

Immunocytochemistry/Immunofluorescence: SNF5 Antibody [H00006598-B01P] - Analysis of purified antibody to SMARCB1 on HeLa cell. (antibody concentration 10 ug/ml)

Immunohistochemistry-Paraffin: SNF5 Antibody [H00006598-B01P] - Analysis of purified antibody to SMARCB1 on formalin-fixed paraffin-embedded human esophagus. (antibody concentration 3 ug/ml)

Western Blot: SNF5 Antibody [H00006598-B01P] - Analysis of SMARCB1 expression in transfected 293T cell line by SMARCB1 polyclonal antibody. Lane 1: SMARCB1 transfected lysate(42.35 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

SNF5 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SMARCB1 (NP_003064.2, 1 a.a. - 385 a.a.) full-length human protein. MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW
• Specificity: SMARCB1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: SMARCB1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control. It has been used for IHC-P and IF.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SNF5 Antibody

• BAF47
• BAF47hSNF5
• BRG1-associated factor 47
• hSNFS
• Ini1
• INI1RTPS1
• Integrase interactor 1 protein
• malignant rhabdoid tumor suppressor
• RDTSNF5 homolog
• Sfh1p
• SNF5
• SNF5L1
• Snr1
• subfamily b, member 1
• sucrose nonfermenting, yeast, homolog-like 1
• SWI/SNF related, matrix associated, actin dependent regulator of chromatin
• SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily B member 1

Background

The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SNF5 Antibody (H00006598-B01P)(1)

Publication using H00006598-B01P

• Izumi T, Kawahara E, Oyama T, and Goi T SMARCB1- and vimentin-positive esophageal carcinoma with undifferentiated components, rhabdoid features, and a good prognosis: a case report. Surg Case Rep. 2019-04-02 [PMID: 30649642]

Bioinformatics

• Gene Symbol: SMARCB1
• Entrez:
  • 6598(Human)
• Uniprot:
  • NP_003064.2(Human)