SMARCA1 Recombinant Enzymes

• Reactivity: Hu
• Applications: NULL

SMARCA1 Recombinant Enzymes Summary

• Description: Human SNF2L (aa 2-1054) fused to a FLAG-tag at the N-terminus. (Uniprot: P28370-1)
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Enzymes
• Gene: SMARCA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • N/A

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for SMARCA1 Recombinant Enzymes

• ATP-dependent helicase SMARCA1
• DKFZp686D1623
• EC 3.6.1
• EC 3.6.4.-
• FLJ41547
• global transcription activator homologous sequence
• Nucleosome-remodeling factor subunit SNF2L
• NURF140
• probable global transcription activator SNF2L1
• SNF2L
• SNF2L1ISWI
• SNF2LB
• SNF2-like 1
• SNF2LT
• subfamily a, member 1
• sucrose nonfermenting 2-like protein 1
• SWI
• SWI/SNF related, matrix associated, actin dependent regulator of chromatin
• SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a1
• SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 1
• SWI2

Background

The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. Member of this family have helicase and ATPase activities that alter chromatin structure to facilitate gene transcription. SMARCA1/SNF2L is a component of the human NURF (nucleosome remodeling factor) involved in the regulation of genes involved in neuronal development. SMARCA1/SNF2L is also a component of the heterodimeric complex CERF [CECR2(cat eye syndrome chromosome region, candidate 2)-containing remodeling factor]. Alternate names for SMARCA1/SNF2L include SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a1, SNF2, SNF2L, SNF2L1, SNF2LB, sucrose nonfermenting 2-like protein 1, NURF140, and ISWI.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SMARCA1