SLPI Recombinant Protein Summary
A recombinant protein with a His tag and corresponding to amino acids 26 - 132 of SLPI.
Source: E. coli
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSGKSFKAGV CPPKKSAQCL RYKKPECQSD WQCPGKKRCC PDTCGIKCLD PVDTPNPTRR KPGKCPVTYG QCLMLNPPNF CEMDGQCKRD LKCCMGMCGK SCVSPVKA
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 100mM NaCl.
The purity of this protein is > 80% by SDS-PAGE. Molecular weight is 14.0kDa (128aa) confirmed by MALDI-TOF The His tag increases overall size to 128 residues.
Alternate Names for SLPI Recombinant Protein
- ALPProtease inhibitor WAP4
- BLPISeminal proteinase inhibitor
- Mucus proteinase inhibitor
- secretory leukocyte peptidase inhibitor
- secretory leukocyte protease inhibitor (antileukoproteinase)
- Secretory leukocyte protease inhibitor
- WAP four-disulfide core domain protein 4
SLPI is a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity. Recombinant human SLPI, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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