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SLPI encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity.
|Product By Gene ID
- secretory leukocyte protease inhibitor (antileukoproteinase)
- Secretory leukocyte protease inhibitor
- WAP four-disulfide core domain protein 4
- BLPISeminal proteinase inhibitor
- ALPProtease inhibitor WAP4
- Mucus proteinase inhibitor
- secretory leukocyte peptidase inhibitor
Research Areas for SLPI
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Bioinformatics Tool for SLPI
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