SLPI Products

Description

SLPI encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity.

Bioinformatics

Entrez	6590 Human
Uniprot	AAH20708 Human ABM85471.1 Human CAA28187 Human NM_003064 Human NP_003055 Human P03973 Human
Product By Gene ID	6590
Alternate Names	ALK1 ALPProtease inhibitor WAP4 antileukoproteinase BLPISeminal proteinase inhibitor HUSI HUSI-I Mucus proteinase inhibitor secretory leukocyte peptidase inhibitor secretory leukocyte protease inhibitor (antileukoproteinase) Secretory leukocyte protease inhibitor WAP four-disulfide core domain protein 4 WAP4HUSI-1 WFDC4MPI

Research Areas for SLPI

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Cancer