SLC22A2/OCT2 Antibody (640438) [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Clone: 640438
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

SLC22A2/OCT2 Antibody (640438) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human SLC22A2 in direct ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLC22A2/OCT2 Antibody (640438) [Alexa Fluor™ Plus 555]

• hOCT2
• MGC32628
• OCT2
• OCT2Organic cation transporter 2
• SLC22A2
• solute carrier family 22 (organic cation transporter), member 2
• solute carrier family 22 member 2

Background

Solute carrier family 22 member 2 (SLC22A2; also hOCT2) is a 65 kDa member of the major facilitator superfamily and organic cation transporter family of proteins.   Human SLC22A2 is synthesized as a multipass transmembrane protein that is 555 amino acids (aa) in length.  Human SLC22A2 contains one potential site for N-linked glycosylation.  There are also two additional isoforms for human SLC22A2.   Isoform 2 has a 57 aa substitution for aa 427-483 and a deletion of the 72 aa at positions 484-555.   Isoform 3 has an 18 aa substitution for aa 225-242 and a deletion of residues 243-555.  SLC22A2 has its highest expression in the kidney.  It is also expressed at lower levels in neurons of the cerebral cortex and in various subcortical nuclei.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.