SIVA Antibody (OTI2F8) [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clone: OTI2F8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

SIVA Antibody (OTI2F8) [Janelia Fluor® 646] Summary

• Immunogen: Full length recombinant protein of human SIVA (NP_006418) produced in HEK293T cells.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SIVA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SIVA Antibody (OTI2F8) [Janelia Fluor® 646]

• CD27-binding (Siva) protein
• CD27BPCD27-binding protein
• Siva-1
• SIVA1, apoptosis-inducing factor
• Siva-2
• SIVAapoptosis regulatory protein Siva

Background

SIVA encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIVA1