SIRT2 (AAH03012, 128 a.a. ~ 227 a.a) partial recombinant protein with GST tag.YTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSL
Cytoplasmic for short periods of time until complexes are formed (Sir2, Sir3 and Sir4). The complexes are recruited to their chromosome targets (nuclear) via interactions with DNA binding proteins, followed by deacetylation of histones H3 and H4. Therefor
Early Oligodendrocyte Marker
SIRT2 - sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
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Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Sirtuin 2/SIRT2 Antibody (4B11)
S.cerevisiae, homolog) 2
sirtuin type 2
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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