SIRP gamma/CD172g Antibody (595337) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 595337
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

SIRP gamma/CD172g Antibody (595337) [Alexa Fluor® 488] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human SIRP gamma /CD172g
  Val64-Ser364
  Accession # Q9P1W8
• Specificity: Detects human SIRP gamma /CD172g in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 20% cross-reactivity with recombinant human (rh) SIRP alpha and rhSIRP beta 1 is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SIRP gamma/CD172g Antibody (595337) [Alexa Fluor® 488]

• bA77C3.1
• CD172g antigen
• CD172g
• FLJ42230
• signal-regulatory protein beta 2
• Signal-regulatory protein beta-2
• signal-regulatory protein gamma
• SIRP beta 2
• SIRP gamma
• SIRP-B2
• SIRPB2CD172 antigen-like family member B
• SIRP-beta-2
• SIRPG
• SIRPgamma
• SIRP-gamma

Background

Signal-regulatory protein gamma/beta 2 (SIRP gamma/beta 2) is a 45-47 kDa type 1 transmembrane glycoprotein and member of the immunoglobulin superfamily and SIRP family of proteins. Human SIRP gamma/beta 2 is synthesized as a 387 amino acid (aa) precursor that contains a 28 aa signal sequence, a 332 aa extracellular domain (ECD), a 23 aa transmembrane segment, and a 4 aa cytoplasmic tail. The ECD contains two Ig-like C1-type domains, one Ig-like V-type domain, and four potential sites for N-linked glycosylation. There are four named isoforms for human SIRP gamma/beta 2. Human SIRP gamma/beta 2 has no orthologs, but it is 75% aa identical to SIRP beta . It is expressed in the liver and at very low levels in brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRP gamma/beta 2 is also expressed on CD4⁺ T-cells, CD8⁺ T-cells, and activated NK cells. 

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q9P1W8()