Shugoshin Antibody

Western Blot: Shugoshin Antibody [H00151648-D01P] - Analysis of SGOL1 expression in transfected 293T cell line by SGOL1 polyclonal antibody.Lane 1: SGOL1 transfected lysate(33.50 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Shugoshin Antibody Summary

• Immunogen: SGOL1 (NP_612493.1, 1 a.a. - 292 a.a.) full-length human protein. MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDNNKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSSGMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEATPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEVSPAKEAIFILYYVREFVSRFPDCRKCKLETHICLR
• Specificity: SGOL1 - shugoshin-like 1 (S. pombe),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SGO1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Shugoshin Antibody

• FLJ14230
• hSgo1
• NY-BR-85
• Serologically defined breast cancer antigen NY-BR-85
• SGO
• Sgo1
• shugoshin 1AB protein
• shugoshin 1CD protein
• shugoshin 1EF protein
• shugoshin 1GH protein
• shugoshin 1KL protein
• shugoshin-like 1 (S. pombe)
• shugoshin-like 1

Background

Shugoshin (Sgo) proteins constitute a conserved protein family defined as centromeric protectors of Rec8-containing cohesin complexes in meiosis. It has been demonstrated that vertebrate shugoshin is required for preserving centromeric cohesion during mitosis. The presence of human Scc1 at centromeres in mitosis is dependent on human Sgo1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SGO1
• Entrez:
  • 151648(Human)
• Uniprot:
  • NP_612493.1(Human)