Human SHBG ELISA Kit (Colorimetric)

• Reactivity: Hu
• Applications: ELISA, NULL
• Suitable Sample Type: Plasma (Heparin), Serum
• Standard Curve Range: 0.77 to 260 nmol/L
• Sensitivity: 0.77 nmol/L

Human SHBG ELISA Kit (Colorimetric) Summary

• Description: SHBG (Human) ELISA Kit is an enzyme immunoassay for the quantitative measurement of SHBG in human serum.
• Standard Curve Range: 0.77 to 260 nmol/L
• Sensitivity: 0.77 nmol/L
• Assay Type: Quantification
• Inter-Assay: CV% < 8.975%
• Intra-Assay: CV% < 5.3%
• Spike Recovery: 100.02%
• Sample Volume: 20 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: SHBG

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification

Packaging, Storage & Formulations

• Storage: Store at 4C.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human SHBG ELISA Kit (Colorimetric)

• ABP
• ABPTestosterone-estrogen-binding globulin
• androgen binding protein
• MGC126834
• MGC138391
• SBP
• sex hormone-binding globulin
• Sex steroid-binding protein
• SHBG
• TEBG
• Testis-specific androgen-binding protein
• testosterone-binding beta-globulin
• Testosterone-estradiol-binding globulin

Background

The gene encodes an EF hand-containing small calcium binding protein. It is an integral subunit component of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Kv4 potassium channels regulate action potentials in neurons and cardiac myocytes. The coexpression of ABP with pore-forming Kv4 alpha subunits causes changes in the gating and amplitude of Kv4 currents, thus profoundly affect the intracellular trafficking and molecular properties of Kv4.2 alpha subunits. It also cause a dramatic redistribution of Kv4.2, releasing intrinsic endoplasmic reticulum retention and allowing for trafficking to the cell surface. It may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. It maps to 5q35.1 region of human chromosome. Alternative splicing results in multiple transcript variant encoding different isoforms. Isoform 1 and isoform 2 are expressed in brain and kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: SHBG