SerpinB2 Antibody (930109) [Unconjugated] Summary
E. coli-derived recombinant human Serpin B2
Accession # P05120
Detects human Serpin B2 in direct ELISAs.
Protein A or G purified from hybridoma culture supernatant
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Flow Cytometry 0.25 ug/10^6 cells
- Immunocytochemistry 8-25 ug/mL
- Knockout Validated
- Western Blot 2 ug/mL
Packaging, Storage & Formulations
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for SerpinB2 Antibody (930109) [Unconjugated]
- Monocyte Arg-serpin
- PAI2Urokinase inhibitor
- Placental plasminogen activator inhibitor
- plasminogen activator inhibitor 2
- plasminogen activator inhibitor, type II (arginine-serpin)
- serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
- Serpin B2
- serpin peptidase inhibitor, clade B (ovalbumin), member 2
- Urokinase Inhibitor
Serpin B2, also known as Plasminogen Activator Inhibitor 2 (PAI-2), is a 415 amino acid serine-type endopeptidase inhibitor with high expression in blood, vasculature and placenta. Its expression is upregulated in pregnancy and in activated monocytes/macrophages by a wide range of viral, bacterial and parasitic agents. Serpin B2 is upregulated in monocytes from HIV-1 infected patients, and is thought to modulate Th1/Th2 responses. Serpin B2/PAI-2 colocalizes with CHL1 and Vitronectin and mediates neurite outgrowth during post-natal brain development. Inhibition of uPA by SerpinB2 in tumors is associated with a favorable prognosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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