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Serpin B5/Maspin Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, KO
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Allophycocyanin
AF2218A
CoraFluor 1
AF2218CL1
DyLight 350
AF2218D
DyLight 405
AF2218E
DyLight 488
AF2218K
DyLight 550
AF2218L
DyLight 594
AF2218M
DyLight 650
AF2218W
DyLight 680
AF2218Y
DyLight 755
AF2218Z
FITC
AF2218F
HRP
AF2218H
Janelia Fluor 525
AF2218JF525
Janelia Fluor 549
AF2218I
Janelia Fluor 646
AF2218J
Janelia Fluor 669
AF2218JF669
PE
AF2218P
PerCP
AF2218C
Unconjugated
AF2218
mFluor Violet 450 SE
AF2218MFV450
mFluor Violet 500 SE
AF2218MFV500
mFluor Violet 610 SE
AF2218MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF2218
Carrier Free
AF2218
Carrier Free
AF2218-SP
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Serpin B5/Maspin Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human Serpin B5/Maspin
Met1-Pro375
Accession # P36952
Specificity
Detects human Serpin B5/Maspin in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3, rhSerpin A4, rhSerpin A5, rhSerpin C1, rhSerpin F2, rhSerpin I1, rhSerpin I2, rhPEDF, and recombinant mouse Serpin D1 is observed.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SERPINB5
Purity
Antigen Affinity-purified
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Applications/Dilutions

Dilutions
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Antigen Affinity-purified

Alternate Names for Serpin B5/Maspin Antibody [Biotin]

  • Maspin
  • Peptidase inhibitor 5
  • PI5
  • PI-5
  • PI5protease inhibitor 5 (maspin)
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
  • Serpin B5
  • serpin peptidase inhibitor, clade B (ovalbumin), member 5

Background

Maspin is an extracellular matrix tumor supressor that blocks the growth, invasion, and metastatic properties of mammary and prostate tumors. Structurally Maspin is a serine protease inhibitor (Serpin), but it does not undergo the stressed to relaxed conformational transition characteristic of active serpins and exhibits no serine protease inhibitory activity. Maspin is also expressed by the corneal epithelium and regulates migration and adhesion of corneal stromal fibroblasts and myofibroblasts during corneal wound healing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINB5