Serpin A7/TBG Antibody

Western Blot: Serpin A7/TBG Antibody [H00006906-D01P] - Analysis of SERPINA7 expression in transfected 293T cell line by SERPINA7 polyclonal antibody.Lane 1: SERPINA7 transfected lysate(46.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Serpin A7/TBG Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SERPINA7 (AAH20747.1, 1 a.a. - 415 a.a.) full-length human protein. MSPFLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA
• Specificity: SERPINA7 - serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SERPINA7
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Serpin A7/TBG Antibody

• antitrypsin), member 7
• FLJ17820
• member 7
• Serpin A7
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
• T4-binding globulin
• TBG
• TBGclade A (alpha-1 antiproteinase
• thyroxin-binding globulin
• thyroxine-binding globulin

Background

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINA7
• Entrez:
  • 6906(Human)
• Uniprot:
  • AAH20747.1(Human)