Serpin A6/Cortisol Binding Globulin Antibody (433903) [Alexa Fluor® 750]

• Reactivity: Mu
• Applications: WB
• Clone: 433903
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 750

Serpin A6/Cortisol Binding Globulin Antibody (433903) [Alexa Fluor® 750] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Serpin A6
  Val23-Ala397
  Accession # Q06770
• Specificity: Detects mouse Serpin A6 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse Serpin A1, A5, B8, C1, D1, E1, E2, F1, F2, I1, recombinant human Serpin A3, A4, B6, B9, G1, I2, or recombinant rat Serpin A6 is o
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serpin A6/Cortisol Binding Globulin Antibody (433903) [Alexa Fluor® 750]

• antitrypsin), member 6
• CBG
• CBGcorticosteroid-binding globulin
• corticosteroid binding globulin
• member 6
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• Serpin A6
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
• transcortin

Background

Serpin A6 (also known as corticosteroid-binding globulin/CBG and Transcortin) is a 50‑60 kDa, secreted glycoprotein member of the serpin family of protease inhibitors. It is produced by hepatocytes and transports > 90% of circulating cortisol. Although Serpin A6 is a serpin family member, it shows no protease inhibition. Mature mouse Serpin A6 is 375 amino acids (aa) in length. Over aa 23‑397, mouse Serpin A6 shares 78% and 57% aa sequence identity with rat and human Serpin A6, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.