Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6)

Western Blot: Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6) [H00000012-M01] - Analysis of SERPINA3 expression in transfected 293T cell line by SERPINA3 monoclonal antibody (M01), clone 1E6.Lane 1: SERPINA3 transfected lysate(47.7 KDa).Lane 2: Non-transfected lysate.

Immunohistochemistry-Paraffin: Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6) [H00000012-M01] - Analysis of monoclonal antibody to SERPINA3 on formalin-fixed paraffin-embedded human ovary, clear cell carcinoma. Antibody concentration 1 ug/ml.

Western Blot: Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6) [H00000012-M01] - Analysis of SERPINA3 transfected lysate using anti-SERPINA3 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SERPINA3 MaxPab rabbit polyclonal antibody.

ELISA: Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6) [H00000012-M01] - Detection limit for recombinant GST tagged SERPINA3 is 1 ng/ml as a capture antibody.

Product Discontinued

Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: SERPINA3 (AAH03559, 25 a.a. ~ 423 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA
• Specificity: SERPINA3 - serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERPINA3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot 1:500
• Application Notes: Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Serpin A3/alpha 1-Antichymotrypsin Antibody (1E6)

• AACTMGC88254
• ACTGIG25
• alpha 1-Antichymotrypsin
• alpha-1-antichymotrypsin
• antitrypsin), member 3
• Cell growth-inhibiting gene 24/25 protein
• growth-inhibiting protein 24
• growth-inhibiting protein 25
• member 3
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• serine (or cysteine) proteinase inhibitor, clade A, member 3
• Serpin A3
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Background

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINA3
• Entrez:
  • 12(Human)
• OMIM:
  • 107280(Human)
• Uniprot:
  • AAH03559(Human)