SERCA2 ATPase Antibody


Western Blot: SERCA2 ATPase Antibody [NB100-237] - Detection of Pig, Rat and Rabbit SERCA2 on HeLa whole cell lysate using NB100-237.

Product Details

Reactivity Hu, Mu, Rt, Po, RbSpecies Glossary
Applications WB, ChIP, IP
1.0 mg/ml

Order Details

SERCA2 ATPase Antibody Summary

The immunogen recognized by this antibody maps to a region between residue 475 and 525 of human ATPase, Ca++ transporter, cardiac muscle, slow twitch 2 using the numbering given in entry NP_733765.1 (GeneID 488).
Endoplasmic reticulum + Sarcoplasmic reticulum membrane protein
Predicted Species
Equine (100%), Canine (100%), Chicken (100%), Turkey (100%), Xenopus (100%), Bovine (100%), Guinea Pig (100%), Primate (100%)
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-citrate/phosphate buffer, pH 7 to 8
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified


  • Western Blot 1:1000-1:5000
  • Chromatin Immunoprecipitation 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
This antibody can be used for Western Blot, where a band is seen around 110 kDa. Use in Immunoprecipitation reported in scientific literature (PMID 24284412) Use in chromatin immunoprecipitation reported in scientific literature (PMID 24284412)
Read Publications using
NB100-237 in the following applications:

  • 1 publication
  • 1 publication
  • IP
    1 publication
  • WB
    3 publications

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with X. laevis, X. tropicalis, Chicken, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Duckbill platypus, Tasmanian devil and Northern white-cheeked gibbon.

Alternate Names for SERCA2 ATPase Antibody

  • ATP2BFLJ20293
  • ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  • Calcium pump 2
  • Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform
  • cardiac Ca2+ ATPase
  • DAR
  • DD
  • EC 3.6.3
  • EC
  • Endoplasmic reticulum class 1/2 Ca(2+) ATPase
  • FLJ38063
  • MGC45367
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  • SERCA2DKFZp686P0211
  • SR Ca(2+)-ATPase 2


Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Mu
Applications: WB, ICC
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, PEP-ELISA
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Po, Ca, Ch, GP, Rb, Sh
Applications: WB, B/N, ICC/IF, IHC, IHC-P, IP
Species: Hu
Applications: WB, IHC, ICC
Species: Hu
Applications: WB
Species: Hu, Mu, Rt, Am, Ca, Rb
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Bv(-), Ca(-), Eq(-), Gp(-), Mu(-), Po(-)
Applications: WB, ELISA, ICC/IF, IP
Species: Hu
Applications: WB
Species: Hu, Mu, Rt
Applications: WB, ELISA
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
Species: Hu
Applications: WB, Simple Western
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P

Publications for SERCA2 ATPase Antibody (NB100-237)(12)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ChIP, ICC/IF, IP, WB.

Filter By Application
All Applications
Filter By Species
All Species
Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using NB100-237 Applications Species
Dunay GA, Paragi P, Sara L et al. Depressed calcium cycling contributes to lower ischemia tolerance in hearts of estrogen-deficient rats. Menopause. 2014 Dec 15 [PMID:25513985] (WB, Rat) WB Rat
Nensa FM, Neumann MH, Schroetter A et al. FE65 interactomics revealed SV2A and SERCA2 as new binding proteins in the human brain. Mol Cell Proteomics. 2013 Nov 27 [PMID:24284412] (WB, ChIP, IP, Human) WB, ChIP, IP Human
Barriga M, Cal R, Cabello N et al. Low Density Lipoproteins Promote Unstable Calcium Handling Accompanied by Reduced SERCA2 and Connexin-40 Expression in Cardiomyocytes PLoS One 2013 [PMID:23516438] (WB, Mouse) WB Mouse
Wang Y, Bruce AT, Tu C et al. Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes. J Cell Sci. 2011 Nov 1 [PMID:22045735] (ICC/IF, Human) ICC/IF Human
Rich S, Pogoriler J, Husain AN et al. Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension. Chest 2010 Nov [PMID:21051399]
Li Q, Hueckstaedt LK, Ren J et al. The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase. Exp Physiol 2009 Sep [PMID:19561140]
Prasad AM, Inesi G. Effects of Thapsigargin Phenylephrine on Calcineurin Protein Kinase C Signaling Functions in Cardiac Myocytes. 2009:00594. 2008 [PMID:19244478]
Song J, Zhang XQ, Wang J et al. Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase. Am J Physiol Heart Circ Physiol 2008 Oct [PMID:18708446]
Leatherbury L, Yu Q, Chatterjee B et al. A novel mouse model of X-linked cardiac hypertrophy. Am J Physiol Heart Circ Physiol;294(6):H2701-2711. 2008 [PMID:18424640]
Yang J, Pawlyk B, Wen XH et al. Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. Hum Mol Genet 2007 May [PMID:17341488]
Show All 12 Publications.

Reviews for SERCA2 ATPase Antibody (NB100-237) (0)

There are no reviews for SERCA2 ATPase Antibody (NB100-237). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ChIP Video Protocol
ChIP Webinar

FAQs for SERCA2 ATPase Antibody (NB100-237) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Additional SERCA2 ATPase Antibody Products

Related Products by Gene

Bioinformatics Tool for SERCA2 ATPase Antibody (NB100-237)

Discover related pathways, diseases and genes to SERCA2 ATPase Antibody (NB100-237). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for SERCA2 ATPase Antibody (NB100-237)

Discover more about diseases related to SERCA2 ATPase Antibody (NB100-237).

Pathways for SERCA2 ATPase Antibody (NB100-237)

View related products by pathway.

PTMs for SERCA2 ATPase Antibody (NB100-237)

Learn more about PTMs related to SERCA2 ATPase Antibody (NB100-237).

Blogs on SERCA2 ATPase.

Mending a Broken Heart: New SERCA2 Gene Therapy Fights Heart Disease
While many of the proteins on our antibody database are studied in relation to their expression in diseases; others become therapies in their own right. This is the case with SERCA2 (Sarcoplasmic reticulum Calcium-ATPase 2 pump), which recently hit th...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol ATP2A2

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NB100-237 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought