SERCA2 ATPase Products

Description

Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.

Bioinformatics

Entrez	100038308 Rabbit 11938 Mouse 29693 Rat 403878 Canine 488 Human
Uniprot	NP_001672.1 Human NP_733765 Human O46674 Canine P16615 Human
Product By Gene ID	488
Alternate Names	ATP2BFLJ20293 ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 Calcium pump 2 Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform cardiac Ca2+ ATPase DAR DD EC 3.6.3 EC 3.6.3.8 Endoplasmic reticulum class 1/2 Ca(2+) ATPase FLJ38063 MGC45367 sarcoplasmic/endoplasmic reticulum calcium ATPase 2 SERCA2DKFZp686P0211 SR Ca(2+)-ATPase 2

Related SERCA2 ATPase Blog Posts

Check out the latest blog posts on SERCA2 ATPase.

Mending a Broken Heart: New SERCA2 Gene Therapy Fights Heart Disease While many of the proteins on our antibody database are studied in relation to their expression in diseases; others become therapies in their own right. This is the case with SERCA2 (Sarcoplasmic reticulum Calcium-ATPase 2 pump), which recently hit th...    Read more.

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