SAP130 Peptide

• Reactivity: Hu
• Applications: AC

SAP130 Peptide Summary

• Description: A peptide to SF3B3.
• Protein/Peptide Type: Peptide
• Gene: SF3B3

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB100-1077.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Preservative: No Preservative

Alternate Names for SAP130 Peptide

• KIAA0017splicing factor 3b, subunit 3, 130kD
• Pre-mRNA-splicing factor SF3b 130 kDa subunit
• RSE1
• SAP130SAP 130
• SF3B130
• SF3b130pre-mRNA splicing factor SF3b, 130 kDa subunit
• Spliceosome-associated protein 130
• splicing factor 3B subunit 3
• splicing factor 3b, subunit 3, 130kDa
• STAF130

Background

SAP130 encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SF3B3